Severe Food Intolerance 36 year old male Treated with FMTs

European male, 36 years old, refers:
- Diagnosed lactose intolerant 10 years ago
- Diagnosed with celiac disease 2 years ago
- Diagnosed refined sugar and citric acid intolerance 1 year ago
- Diagnosed fructose, starch, yeast, intolerant 5 month ago

After starting with gluten free diet (2 years ago) he lost 12 Kg

He suffers from constant diarrhea or soft stools, with 2 to 6 bowel movements a day. The patient was on a gluten, lactose, fructose, refined sugar, starch, yeast free, citric acid diet. He only ate rice, meat, eggs and a few vegetables 4-5 times a day.

Main complaints:
- unfocused, lack of concentration
- weak, powerless
- irritability, especially to any unusual noise
- unable to gain weight
- multiple food intolerance (more strict than a gluten free diet)
- frequent headaches

When we received the patient at Newbery Medicine on the last week of March 2016 he looked very thin and remarkably weak. His weight was 58 kilos his height 1,80. The rest of the physical examination was normal.

We started treating him with Fecal Microbiota Transplants via colonic enema. He tolerated the procedure very well. We repeated FMTs during five consecutive days. By the end of the week he felt somehow more energetic. He noticed he was constipated, which was unusual for him. He took with him frozen implants to continue doing FMTs at home.

Evolution referred by the patient:
April 8: weight went up to 60 kilos, less headaches and more energy.
April 15: weight 61,5 kilos, tried potatoes and got diarrhea for the first time since starting with FMTs. Trying new foods in very small (almost microscopic) portions.
April 22: weight 61,7 kilos, no headaches, continue trying new foods. Less irritability, ate half a potato with no negative symptoms.
April 30: weight 62,4. Tried new foods with some "brain fog" and fatigue.
May 7: weight 63,2. Feeling much better. Only eating small portions of food remains without negative reactions.
May 21: weight 63,5. Ate more potatoes and no reaction.

One month without FMTs as I am traveling.

July 8: weight 69 kilos (11 kilos above the weight when FMTs started). During my trip I tested many new foods and most of them felt good, I had a couple of days with some loose stools. My chronic fatigue is gone and my fear to fly is also gone. Altogether I think FMTs are working very well.

More information, please contact  info@newberymedicine.com or visit www.newberymedicine.com

Crohn´s Disease In a 4 Year Old Treated with Fecal Microbiota Transplants

Crohn´s Disease In a 4 Year Old Treated with Fecal Microbiota Transplants

Female born by cesarean showing a severe atopic dermatitis at three months and at 6 months starts with bloody diarrhea. She is diagnosed as Crohn's disease as her ileum is severely compromised.Her initial treatment was enteral nutrition, supplements and folic acid until she is almost four years old, she never formed stools and her dermatitis persisted. She did not gain weight and had very low energy. She attended kindergarten but had to take frequent naps as she got exhausted very easily.When she was three and a half years her pediatric gastroenterologist recommended the parents to start with a very strong drug (a biologic) and that is when they decided to try something new they found searching the internet. They found some promising results by transforming the gut bacteria being replaced with healthy bacteria via enema. This is a different treatment choice for Crohn´s disease, disease that medicine still ignores where it comes from and why it stays with the patient for the rest of his days. The parents made a consultation with us and we frankly said we have treated other patients with Crohn´s disease but never did it on someone as young as Paula   (not the real name). We discussed the pros and cons and they decided to try doing Fecal Microbiota Transplants (FMTs) as the risks were minimum and the worst scenario could be that Paula did not get any benefit from the implants.Just to know where Paula´s inflammation status was we performed a fecal test called Fecal Calprotectin that can help us measure the progress or not of her treatment. Her initial value on July 7, 2015 was 779 units (normal value less than 50).Our first treatment was on August 27, 2015. The technique is quite simple and very well tolerated, it is performed through a very thin rectal catheter that reaches very high in her descending colon where we implant bacteria from a health donor that has been thoroughly studied and supervised every 60 days.We did daily implants for more than a month and around that time her mother noticed a marked improvement in her energy levels, her skin cleared, the dermatitis almost disappeared and her stools were gaining consistency. Five months later she is getting one FMT per week and her Fecal calprotectin is consistently low In the value of 130 units). She gained weight and has a normal child life, her hair got much better and never suffered again from her dermatitis.

   This is how Paula´s belly looks today, a normal flat belly

One very interesting feature we noticed was that she showed a very distended and tense belly before the treatment, nowadays her belly is totally flat and we can examine her gut with no difficult. Her appetite has increased and enjoys any meal as opposed before when she felt no enthusiasm about any food-

 

 



Persistent Fistula in a 25 years old Male with a Colectomy and Pouch Treated with Fecal Microbiota Transplants



Initial situation November 17, 2015

Persistent Fistula in a 25 years old Male with a Colectomy and Pouch Treated with Fecal Microbiota TransplantsPatient with Ulcerative colitis since he was 15 years old. Treated with many drugs without any positive response. At the age of 18 he undergoes a total colectomy with ileal pouch anal anastomosis (IPAA) or "J" Pouch. Since the first year postop he developed a "pouchitis" that needed the usage of antibiotics on a permanent base.
He consulted with us because now he has a fistula and an a perianal abscess that does not respond to any surgical or medical approach. When we examined the zone we found a deep open abscess with purulent content and a seton drainage connecting the fistula and the rectal cavity.

 Initial situation November 17, 2015

We started to perform Fecal Microbiota Transplants (FMT) via rectal catheter, the antibiotics were interrupted 10 days before the first procedure. The FMTs were performed every day.
There were no side effects nor aggravation of his symptoms.

 Evolution on December 3, 2015, less drainage

 Evolution on December 11, 2015, the abscess is almost totally covered with new tissue and the seton can be freely moved without purulent material.

 Final phase, January 4. A week later the seton is removed. The patient felt his initial symptoms related to the abscess and the fistula were relieved, the pouchitis persisted although he saw some improvements during the treatment with FMTs.